Can You Have Profhilo and Fillers Together?

We get it! You’re a skin care addict (so are we), but can you have Profhilo and fillers together?

Today, in this quick tip we discover the risks vs rewards of combining these treatments and if you should in the first place.

Can You Combine Profhilo and Fillers?

The short answer is yes! But it depends.

Combining these treatments during the same appointment is safe and often encouraged by some practitioners.

Both treatments are hyaluronic acid and will work together to give a great result.

If it’s your first time with these treatments, we recommend you stick with one.

With all injectable treatments you really want to see what treatment works well for you.

If you’re combining treatments, you’ll have no way to tell which treatment gave you the best results.

How Can Profhilo and Dermal Fillers Work Together?

Both injectable treatments are hyaluronic acid, but they work in a completely different way to each other.

Profhilo will help improve the appearance of the skin while dermal fillers will address any loss of volume (sagging skin).

If you’re currently unhappy with the appearance of your skin AND the general shape of your face (due to loss of volume), then combining these treatments will give you the biggest bang for your buck outside of an invasive cosmetic surgery.

If They’re Both Hyaluronic Acid, How Are They Different?

We know it’s confusing, but there are a number of key differences between them.

Molecular structure

Profhilo uses a unique hybrid complex of high molecular weight and low molecular weight hyaluronic acid, while derma filler uses cross-linked hyaluronic acid which is thicker and gel-like.


Profhilo has a higher concentration without the added viscosity from cross-linking, making it better for skin hydration and texture improvement, while dermal fillers are concentrated in a single area for increasing facial volume.


Profhilo is designed for bio-remodelling of the skin, improving its overall quality, elasticity, and texture, while dermal fillers are targeted at filling of wrinkles and hollow areas of the face to provide immediate results.


Profhilo will last around 6 months with treatment requiring 2 sessions spaced one month apart. Fillers can last anywhere from 6 months to 2 years depending on the type used.

Application Method

Profhilo involves fewer injection points and spreads to cover a large area of the face or neck while dermal filler is applied directly into the area that needs volume or correction, requiring precise placement.

Side Effects

Profhilo, in general will have fewer side effects and less downtime compared to fillers due to its more diffuse distribution. For a list of Profhilo side effects check out the article Profhilo Gone Wrong.


Combining Profhilo treatment and dermal fillers together is a great option for people looking for advanced results with what will feel like one injectable treatment (when combined).

It will differ from general anti wrinkle injections plus improve skin laxity as well as stimulate collagen and elastin production.

Initial treatments are best done alone so you can assess the results but if you have a clear loss of volume then combining the treatments from the get-go is fine.

If you’ve tried skin boosters or other injectable treatments that increase collagen production, then these two skin ageing treatments (also known as an anti-ageing treatment) combined together will give amazing initial results to improve skin texture, skin elasticity and dull skin.

Find a Profhilo Location Near You

We have the scoop when it comes to the best locations for Profhilo and Dermal Filler.
Click Here For a Profhilo Location Near You.